here is a specific note from research paper below, i am highlighting as i think this concept will be important in future discussions on the vitamin D topic as we learn that todays knowledge is not the same as tomorrow's knowledge... vitamin D2 is just starting to be studied ect.....
In mammalian research other vitamin D3 metabolites, such as 1,25(OH)2-3-epi-D3 (Brown et al. 1999), and C23 epimers (Lee et al. 2000), and P450 cytochromes involved in their synthesis have been identified (e.g. Bouillon et al. 1995; Tuckey et al. 2008). Understanding the role of these metabolites can, e.g. assist medical research to develop new vitamin D3 analogues. In research on fishes, the development of specific vitamin D3 analogues has received no priority. However, for the understanding of the complexity of the vitamin D endocrine system, it is important to realize that many more metabolites of vitamin D3 than described above may exist in fish and could be of physiological significance. A picture that emerges in other steroids and in thyroid hormones (THs) (Moreno et al. 2008), where multiple TH derivatives have metabolic effects, seems to apply for vitamin D3 as well.
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